A young child who suffers from a metabolic disease is always tired and fatigued

Papers of particular interest, published recently, have been highlighted as:

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Which organelle is most likely responsible for the decreased energy and weakness?

Which of the following is the smallest biological structure that would be visible with a standard research grade light microscope?

Which of the following processes will be unaffected in cells treated with cytochalasin D?

Which organelle is most likely affected when an animal ingests cyanide resulting in decrease in ATP synthesis and oxygen consumption?