Topic Resources Disseminated intravascular coagulation is a condition in which small blood clots develop throughout the bloodstream, blocking small blood vessels. The increased clotting depletes the platelets and clotting factors needed to control bleeding, causing excessive bleeding. There are a number of possible causes, including infection, surgery, and complications of childbirth. Excessive clotting is followed by excessive bleeding. The amount of clotting factors in the blood is measured. The underlying disorder is treated. Disseminated intravascular coagulation
(DIC) begins with excessive clotting How Blood Clots
Hemostasis is the body's way of stopping injured blood vessels from bleeding. Hemostasis includes clotting of the blood. Too little clotting can cause excessive bleeding from minor injury Too... read more . The excessive clotting is usually stimulated by a substance that enters the blood as part of a disease (such as an infection or certain cancers) or as a complication of childbirth, retention of a dead fetus, or surgery. People who have a severe
head injury or who have tissue damage caused by shock
Shock Shock is a life-threatening condition in which blood flow to the organs is low, decreasing delivery of oxygen and thus causing organ damage and sometimes death. Blood pressure is usually low... read more ,
burns Burns Burns are injuries to tissue that result from heat, electricity, radiation, or
chemicals. Burns cause varying degrees of pain, blisters, swelling, and skin loss. Small, shallow burns may need... read more DIC may develop
Slowly developing disseminated intravascular coagulation typically results from cancer, aneurysms, or cavernous hemangiomas (collections of dilated blood vessels). DIC that develops suddenly usually causes bleeding, which may be severe. If the condition follows surgery or childbirth, bleeding may be uncontrollable. Bleeding may occur at the site of an intravenous injection or in the brain, digestive tract, skin, muscles, or cavities of the body.
Blood tests may show that the number of platelets in a blood sample has dropped (platelets are used up when blood clots) and that the blood is taking a long time to clot. The diagnosis of DIC is confirmed if test results show abnormally increased quantities of plasma D-dimer (a substance that blood clots release when they break down; more D-dimer indicates that more clots are being produced than usual) and often a low or decreasing level of fibrinogen (a protein that is consumed when blood clots).
The underlying disorder must be identified and corrected, whether it is an obstetric problem, an infection, or a cancer. The clotting problems subside when the cause is corrected. DIC that develops suddenly is life threatening and is treated as an emergency. Platelets and clotting factors are transfused to replace those depleted and to stop bleeding. Heparin may be used to slow the clotting in people who have more chronic, milder DIC in which clotting is more of a problem than bleeding. CLICK HERE FOR THE PROFESSIONAL VERSION  Copyright © 2022 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. All rights reserved. Which condition may contribute to the development of disseminated intravascular?When you are injured, proteins in the blood that form blood clots travel to the injury site to help stop bleeding. If these proteins become abnormally active throughout the body, you could develop DIC. The underlying cause is usually due to inflammation, infection, or cancer.
What causes disseminated intravascular coagulation?Disseminated intravascular coagulation has been linked to certain medical treatments or conditions. Medical treatments that can cause DIC include: Blood transfusion reactions. Recent surgery or anesthesia.
Which condition is most commonly associated with DIC in pregnancy?In the obstetric population, the most frequent causes of DIC are preeclampsia, placental abruption, sepsis, retained dead fetus syndrome, postpartum hemorrhage, acute fatty liver of pregnancy, and amniotic fluid embolism (Fig. 44.3).
Which client would be most at risk for developing disseminated intravascular coagulation?People who have one or more of the following conditions are most likely to develop DIC: Sepsis (an infection in the bloodstream) Surgery and trauma. Cancer.
Which event that occurs during disseminated intravascular coagulation DIC may predispose a patient to hemorrhage?Consumption of clotting factors and platelets in DIC can result in life-threatening hemorrhage. Derangement of the fibrinolytic system further contributes to intravascular clot formation, but in some cases, accelerated fibrinolysis may cause severe bleeding.
Which occurrence is a manifestation of disseminated intravascular coagulation?With acute DIC, blood clotting in the blood vessels usually occurs first, followed by bleeding. However, bleeding may be the first obvious sign. Serious bleeding can occur very quickly after developing acute DIC.
|
Which condition may contribute to the development of disseminated intravascular coagulation?
zusammenhängende Posts
Urheberrechte © © 2024 ihoctot Inc.
