A nurse is caring for a client who is receiving IV ampicillin and develops urticaria and dyspnea

  • aclidinium

    atropine IV/IM and aclidinium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • amantadine

    atropine IV/IM, amantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Enhanced CNS side effects.

  • amitriptyline

    atropine IV/IM and amitriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • amoxapine

    atropine IV/IM and amoxapine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • anticholinergic/sedative combos

    anticholinergic/sedative combos and atropine IV/IM both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • aripiprazole

    aripiprazole increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of aripiprazole by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of aripiprazole by pharmacodynamic antagonism. Use Caution/Monitor.

  • atracurium

    atracurium and atropine IV/IM both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • belladonna alkaloids

    atropine IV/IM and belladonna alkaloids both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • belladonna and opium

    atropine IV/IM and belladonna and opium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • benperidol

    benperidol increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of benperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of benperidol by pharmacodynamic antagonism. Use Caution/Monitor.

  • benztropine

    atropine IV/IM and benztropine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • bethanechol

    bethanechol increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • carbachol

    carbachol increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • cevimeline

    cevimeline increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • chlorpromazine

    chlorpromazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of chlorpromazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of chlorpromazine by pharmacodynamic antagonism. Use Caution/Monitor.

  • cisatracurium

    atropine IV/IM and cisatracurium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • clomipramine

    atropine IV/IM and clomipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • clozapine

    clozapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of clozapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of clozapine by pharmacodynamic antagonism. Use Caution/Monitor.

  • cyclizine

    atropine IV/IM and cyclizine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • cyclobenzaprine

    atropine IV/IM and cyclobenzaprine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • darifenacin

    atropine IV/IM and darifenacin both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • desipramine

    atropine IV/IM and desipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • dicyclomine

    atropine IV/IM and dicyclomine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • digoxin

    atropine IV/IM increases levels of digoxin by unknown mechanism. Use Caution/Monitor.

  • diphenhydramine

    atropine IV/IM and diphenhydramine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • donepezil

    donepezil increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • dosulepin

    atropine IV/IM and dosulepin both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • doxepin

    atropine IV/IM and doxepin both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • droperidol

    droperidol increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of droperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of droperidol by pharmacodynamic antagonism. Use Caution/Monitor.

  • echothiophate iodide

    echothiophate iodide increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • fesoterodine

    atropine IV/IM and fesoterodine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • flavoxate

    atropine IV/IM and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • fluphenazine

    fluphenazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of fluphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of fluphenazine by pharmacodynamic antagonism. Use Caution/Monitor.

  • galantamine

    galantamine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • glycopyrrolate

    atropine IV/IM and glycopyrrolate both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • glycopyrrolate inhaled

    atropine IV/IM and glycopyrrolate inhaled both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • haloperidol

    haloperidol increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of haloperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of haloperidol by pharmacodynamic antagonism. Use Caution/Monitor.

  • henbane

    atropine IV/IM and henbane both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • homatropine

    atropine IV/IM and homatropine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • huperzine A

    huperzine A increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • hyoscyamine

    atropine IV/IM and hyoscyamine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • iloperidone

    iloperidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of iloperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of iloperidone by pharmacodynamic antagonism. Use Caution/Monitor.

  • imipramine

    atropine IV/IM and imipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • ipratropium

    atropine IV/IM and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • levodopa

    atropine IV/IM, levodopa. Other (see comment). Use Caution/Monitor. Comment: Anticholinergic agents may enhance the therapeutic effects of levodopa; however, anticholinergic agents can exacerbate tardive dyskinesia. In high dosage, anticholinergics may decrease the effects of levodopa by delaying its GI absorption. .

  • lofepramine

    atropine IV/IM and lofepramine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • loxapine

    loxapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of loxapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of loxapine by pharmacodynamic antagonism. Use Caution/Monitor.

  • loxapine inhaled

    loxapine inhaled increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of loxapine inhaled by pharmacodynamic antagonism. Use Caution/Monitor.

  • maprotiline

    atropine IV/IM and maprotiline both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • meclizine

    atropine IV/IM and meclizine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • methscopolamine

    atropine IV/IM and methscopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • neostigmine

    neostigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • nortriptyline

    atropine IV/IM and nortriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • olanzapine

    olanzapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of olanzapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of olanzapine by pharmacodynamic antagonism. Use Caution/Monitor.

  • onabotulinumtoxinA

    atropine IV/IM and onabotulinumtoxinA both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • orphenadrine

    atropine IV/IM and orphenadrine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • oxybutynin

    atropine IV/IM and oxybutynin both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • oxybutynin topical

    atropine IV/IM and oxybutynin topical both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • oxybutynin transdermal

    atropine IV/IM and oxybutynin transdermal both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • paliperidone

    paliperidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of paliperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of paliperidone by pharmacodynamic antagonism. Use Caution/Monitor.

  • pancuronium

    atropine IV/IM and pancuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • perphenazine

    perphenazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of perphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of perphenazine by pharmacodynamic antagonism. Use Caution/Monitor.

  • physostigmine

    physostigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • pilocarpine

    pilocarpine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • pimozide

    pimozide increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of pimozide by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of pimozide by pharmacodynamic antagonism. Use Caution/Monitor.

  • pralidoxime

    atropine IV/IM and pralidoxime both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • prochlorperazine

    prochlorperazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of prochlorperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of prochlorperazine by pharmacodynamic antagonism. Use Caution/Monitor.

  • promethazine

    promethazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.

  • propantheline

    atropine IV/IM and propantheline both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • protriptyline

    atropine IV/IM and protriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • pyridostigmine

    pyridostigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • quetiapine

    quetiapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of quetiapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of quetiapine by pharmacodynamic antagonism. Use Caution/Monitor.

  • rapacuronium

    atropine IV/IM and rapacuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • rimantadine

    atropine IV/IM, rimantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Enhanced CNS side effects.

  • risperidone

    risperidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of risperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of risperidone by pharmacodynamic antagonism. Use Caution/Monitor.

  • rivastigmine

    rivastigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • rocuronium

    atropine IV/IM and rocuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • scopolamine

    atropine IV/IM and scopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • solifenacin

    atropine IV/IM and solifenacin both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • succinylcholine

    succinylcholine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. .

  • thioridazine

    thioridazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of thioridazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of thioridazine by pharmacodynamic antagonism. Use Caution/Monitor.

  • thiothixene

    thiothixene increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of thiothixene by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of thiothixene by pharmacodynamic antagonism. Use Caution/Monitor.

  • tiotropium

    atropine IV/IM and tiotropium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • tolterodine

    atropine IV/IM and tolterodine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • trazodone

    atropine IV/IM and trazodone both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • trifluoperazine

    trifluoperazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of trifluoperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of trifluoperazine by pharmacodynamic antagonism. Use Caution/Monitor.

  • trihexyphenidyl

    atropine IV/IM and trihexyphenidyl both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • trimipramine

    atropine IV/IM and trimipramine both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • trospium chloride

    atropine IV/IM and trospium chloride both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • umeclidinium bromide

    umeclidinium bromide and atropine IV/IM both decrease cholinergic effects/transmission. Use Caution/Monitor. If possible, avoid coadministration of additional anticholinergic agents

  • vecuronium

    atropine IV/IM and vecuronium both decrease cholinergic effects/transmission. Use Caution/Monitor.

  • ziprasidone

    ziprasidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of ziprasidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of ziprasidone by pharmacodynamic antagonism. Use Caution/Monitor.