atropine IV/IM and aclidinium both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM, amantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Enhanced CNS side effects. atropine IV/IM and amitriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and amoxapine both decrease cholinergic effects/transmission. Use Caution/Monitor. anticholinergic/sedative combos and atropine IV/IM both decrease cholinergic effects/transmission. Use Caution/Monitor. aripiprazole increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of aripiprazole by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of aripiprazole by pharmacodynamic antagonism. Use Caution/Monitor. atracurium and atropine IV/IM both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and belladonna alkaloids both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and belladonna and opium both decrease cholinergic effects/transmission. Use Caution/Monitor. benperidol increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of benperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of benperidol by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and benztropine both decrease cholinergic effects/transmission. Use Caution/Monitor. bethanechol increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . carbachol increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . cevimeline increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . chlorpromazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of chlorpromazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of chlorpromazine by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and cisatracurium both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and clomipramine both decrease cholinergic effects/transmission. Use Caution/Monitor. clozapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of clozapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of clozapine by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and cyclizine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and cyclobenzaprine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and darifenacin both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and desipramine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and dicyclomine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM increases levels of digoxin by unknown mechanism. Use Caution/Monitor. atropine IV/IM and diphenhydramine both decrease cholinergic effects/transmission. Use Caution/Monitor. donepezil increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . atropine IV/IM and dosulepin both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and doxepin both decrease cholinergic effects/transmission. Use Caution/Monitor. droperidol increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of droperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of droperidol by pharmacodynamic antagonism. Use Caution/Monitor. echothiophate iodide increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . atropine IV/IM and fesoterodine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and flavoxate both decrease cholinergic effects/transmission. Use Caution/Monitor. fluphenazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of fluphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of fluphenazine by pharmacodynamic antagonism. Use Caution/Monitor. galantamine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . atropine IV/IM and glycopyrrolate both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and glycopyrrolate inhaled both decrease cholinergic effects/transmission. Use Caution/Monitor. haloperidol increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of haloperidol by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of haloperidol by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and henbane both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and homatropine both decrease cholinergic effects/transmission. Use Caution/Monitor. huperzine A increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . atropine IV/IM and hyoscyamine both decrease cholinergic effects/transmission. Use Caution/Monitor. iloperidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of iloperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of iloperidone by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and imipramine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and ipratropium both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM, levodopa. Other (see comment). Use Caution/Monitor. Comment: Anticholinergic agents may enhance the therapeutic effects of levodopa; however, anticholinergic agents can exacerbate tardive dyskinesia. In high dosage, anticholinergics may decrease the effects of levodopa by delaying its GI absorption. . atropine IV/IM and lofepramine both decrease cholinergic effects/transmission. Use Caution/Monitor. loxapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of loxapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of loxapine by pharmacodynamic antagonism. Use Caution/Monitor. loxapine inhaled increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of loxapine inhaled by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and maprotiline both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and meclizine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and methscopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor. neostigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . atropine IV/IM and nortriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor. olanzapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of olanzapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of olanzapine by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and onabotulinumtoxinA both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and orphenadrine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and oxybutynin both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and oxybutynin topical both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and oxybutynin transdermal both decrease cholinergic effects/transmission. Use Caution/Monitor. paliperidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of paliperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of paliperidone by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and pancuronium both decrease cholinergic effects/transmission. Use Caution/Monitor. perphenazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of perphenazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of perphenazine by pharmacodynamic antagonism. Use Caution/Monitor. physostigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . pilocarpine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . pimozide increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of pimozide by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of pimozide by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and pralidoxime both decrease cholinergic effects/transmission. Use Caution/Monitor. prochlorperazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of prochlorperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of prochlorperazine by pharmacodynamic antagonism. Use Caution/Monitor. promethazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia. atropine IV/IM and propantheline both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and protriptyline both decrease cholinergic effects/transmission. Use Caution/Monitor. pyridostigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . quetiapine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of quetiapine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of quetiapine by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and rapacuronium both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM, rimantadine. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Enhanced CNS side effects. risperidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of risperidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of risperidone by pharmacodynamic antagonism. Use Caution/Monitor. rivastigmine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . atropine IV/IM and rocuronium both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and scopolamine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and solifenacin both decrease cholinergic effects/transmission. Use Caution/Monitor. succinylcholine increases and atropine IV/IM decreases cholinergic effects/transmission. Effect of interaction is not clear, use caution. Use Caution/Monitor. . thioridazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of thioridazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of thioridazine by pharmacodynamic antagonism. Use Caution/Monitor. thiothixene increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of thiothixene by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of thiothixene by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and tiotropium both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and tolterodine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and trazodone both decrease cholinergic effects/transmission. Use Caution/Monitor. trifluoperazine increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of trifluoperazine by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of trifluoperazine by pharmacodynamic antagonism. Use Caution/Monitor. atropine IV/IM and trihexyphenidyl both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and trimipramine both decrease cholinergic effects/transmission. Use Caution/Monitor. atropine IV/IM and trospium chloride both decrease cholinergic effects/transmission. Use Caution/Monitor. umeclidinium bromide and atropine IV/IM both decrease cholinergic effects/transmission. Use Caution/Monitor. If possible, avoid coadministration of additional anticholinergic agents atropine IV/IM and vecuronium both decrease cholinergic effects/transmission. Use Caution/Monitor. ziprasidone increases effects of atropine IV/IM by pharmacodynamic synergism. Use Caution/Monitor. Additive anticholinergic effects, possible hypoglycemia.atropine IV/IM decreases levels of ziprasidone by inhibition of GI absorption. Applies only to oral form of both agents. Use Caution/Monitor.atropine IV/IM decreases levels of ziprasidone by pharmacodynamic antagonism. Use Caution/Monitor. |