In which trimester of pregnancy is the fetus most vulnerable to teratogens quizlet?

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-In general, considered teratogenic
--> 5-10% with a single medication
--> Risk doubles if exposure to two or more medications

-Fetal Anticonvulsant Syndromes (FACS)- dysmorphology, developmental delay, neural tube defects, genitourinary anomalies, limb and heart defects

-Folic acid antagonists; recommend folic acid supplementation

-Recommend vitamin K treatment near term (newborn hemorrhagic disease)

-In 1/3 of cases, seizure activity increases in pregnancy

-Difficulty in balancing teratogenic risks of medications with risks of seizures during pregnancy

*Optimal seizure control is imperative during pregnancy despite teratogenic risks*

-Patients should be encouraged to take meds under care by neurology, maternal-fetal-management specialist

In which trimester of pregnancy is the fetus most vulnerable to teratogens?

The first half of pregnancy is the most vulnerable.

In which trimester of pregnancy is the fetus the most vulnerable to teratogens quizlet?

The developing human is most vulnerable to the effects of teratogens during the period of organogenesis, the first 8 weeks of gestation.

Which trimester is the most critical period for embryo exposure to teratogens?

Harmful exposures during the first trimester have the greatest chance of causing major birth defects. This is because many important developmental changes take place during this time. The major structures of the body form in the first trimester. These include the spine, head, arms and legs.

During which stage of fetal development is exposure to teratogens most damaging quizlet?

- The effects of a teratogenic agent are worst during the critical period when an organ system grows most rapidly. - Organogenesis takes place during the embryonic period (weeks 3-8 of prenatal development).

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